The probable radioprotective role of Acacia nilotica L. against biochemical and cytogenetic disorders induced in gamma irradiated male rats

Gum Arabic (Acacia nilotica L.) is a respected plant that has many nutrients and curative practices. It hinders, improves, or manages disorders. The radio-protective activity of Acacia was investigated against γ-rays-induced testicle damage in rats. Twenty-four rats were correspondingly distributed into 4 groups; control, (15mg/kg, daily for 30 days), γ-irradiated (5Gy γ-rays, single dose) plus γ-rays treated groups. plasma testosterone total antioxidant status (TAS) estimated. Lipid peroxidation; malondialdehyde (MDA), reduced glutathione (GSH), superoxide dismutase (SOD), also peroxidase (GPx), catalase (CAT), tumor necrosis factor-α (TNF-α) with interleukin-1β (IL-1β), determined the tissues. A testis weight, sperm count motility, peripheral-blood bone-marrow micronuclei (PMN BMN), frequency chromosomal aberrations (CAs) scored. significant decline levels TAS observed results showed significantly increased MDA, inflammatory markers, PMN, BMN CAs frequencies decrease testes motility antioxidants markers gamma irradiated group. All these biochemical fertility indices enhanced However, possible alleviate on injury not previously conversed, this topic study.